Red Light Therapy and Fertility Preservation in Women with Cancer

This study caught my eye for several reasons.

Is PBM protective against premature ovarian failure in healthy women?

Is PBM a way to help preserve fertility in women undergoing cancer treatments?

While the effects of aging and certain medical treatments on fertility are well known, new research suggests that light-based therapies may offer a way to support ovarian health and improve fertility outcomes. From this innovative study it seems that photobiomodulation, may reduce damage and support ovarian function in recent studies, providing promising news for women dealing with ovarian challenges. In young female cancer patients, fertility preservation includes embryo and oocyte freezing. But this isn’t optimal for everyone. A new study suggests that PBM could be a simple, affordable and safe approach for women who have contraindications to cryopreservation techniques.

How Photobiomodulation May Protect Ovaries from Damage

A recent study tested PBM on mice exposed to cyclophosphamide, a chemotherapy drug known to damage ovarian tissue, simulating the effects of aging and premature ovarian failure. Researchers discovered that laser helped preserve the ovaries in several important ways:

Hormone Support: PBM boosted serum progesterone levels, a crucial hormone for reproductive health, as well as the total weight of the ovaries, indicating improved ovarian function.

Reduced Cell Death: PBM inhibited apoptosis (cell death) in ovarian tissue, especially in places where eggs mature. This means that fewer healthy cells were lost, maintaining the delicate balance required for fertilization.

Improved Blood Flow: The therapy also improved vascular health in the ovary, which supports healthy blood flow. Improved blood flow ensures the ovaries have enough oxygen and nutrients to operate properly.

What Does This Mean for Women?

These findings are crucial for women dealing with POF, ovarian aging, and cancer treatments. Although PBM has mainly been investigated in other areas such as pain management and wound healing—its impact on reproductive health is gaining more interest around the world. By supporting cellular health, reducing inflammation, and protecting follicles from damage, red light laser therapy could potentially extend our ovarian lifespan or improve ovarian function.

Of course more studies are necessary to fully understand its potential for fertility preservation in women undergoing cancer treatment, PBM may provide a non-invasive option to support ovarian function and improve reproductive outcomes. It’s worth keeping an eye on developments in this area.

Tracy